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[4] [1] The most common injection site reactions include: Erythema (redness) : Localised redness surrounding the injection site, typically appearing within minutes to hours after administration Pruritus (itching) : Mild to moderate itching at or around the injection site Swelling or induration : Raised, firm areas of skin that may persist for several hours Pain or tenderness : Discomfort ranging from mild sensitivity to more pronounced soreness Bruising (ecchymosis) : Small haematomas resulting from minor blood vessel trauma during injection Most injection site reactions develop within 24 hours of administration and resolve within 23 days without specific treatment